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Reproduction Reborn: How Science, Ethics, and Law Shape Mitochondrial Replacement Therapies


ISBN13: 9780197616208
Published: March 2023
Publisher: Oxford University Press
Country of Publication: UK
Format: Paperback
Price: £29.99



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A cutting-edge analysis of the global issues surrounding modern reproductive technologies.
Advances in assisted reproductive technologies have sparked global policy debates since the birth of the first so-called "test tube baby" in 1978. Today, mitochondrial replacement therapies represent the most recent advancement in assisted reproductive technologies, allowing some women with mitochondrial diseases to birth babies without those diseases. In the past decade, mitochondrial replacement therapies have captured public sentiment, reigniting debates around social views of reproductive rights and the appropriate legal and political response.

Reproduction Reborn guides readers through the history and science of mitochondrial replacement therapies and the various attempts to control them. Leading experts from medicine, genetics, ethics, law, and policy explore the influence of public debate on the evolving shape of these technologies and their subsequent regulation. They highlight case studies from both developed and developing countries across the globe, including recent legislation in Australia and China. They further identify the ethical, legal, and societal norms that need to be addressed by policymakers and communities as more and more people seek to gain access to these treatments. Given the importance of reproduction in family life and cultural identity, clinicians and policymakers must understand how regulatory regimes around mitochondrial replacement therapies have evolved to illuminate the processes and challenges of governing reproduction in a fast-moving world.

Informative and global in scope, Reproduction Reborn explores how advancements in assisted reproductive technologies challenge core values surrounding the rights and responsibilities of modern-day family units.

Subjects:
Medical Law and Bioethics
Contents:
List of contributors
Abbreviations
Acknowledgements
Introduction
Diana M. Bowman, Walter G. Johnson, and Karinne Ludlow

Part I: Untangling the Development of Science and Public Opinion Around MRT
1. Development of Mitochondrial Replacement Therapies
Jeffrey R. Mann, Mary Herbert, Deirdre L. Zander-Fox, Deepak Adhikari, and John Carroll
2. Mitochondrial Replacement Techniques: A Critical Review of the Ethical Issues
Robert Sparrow, Julian Koplin, and Catherine Mills
3. Reproductive Decisions and Mitochondrial Disease: Disruption, Risk, and Uncertainty
Cathy Herbrand

Part II: The Evolution of Regulatory Frameworks for MRT: How Regulation Got from There to Here (and Everywhere In-Between)
4. Legalising MRT in the United Kingdom
Rebecca Dimond and Neil Stephens
5. MRT in Australia
Karinne Ludlow
6. MRT in the United States
I. Glenn Cohen, Priyanka Menon, and Eli Y. Adashi
7. Contesting the 'No Rules' Label: ARTs in Mexico Before and After the First MRT Baby
Sandra González-Santos and Abril Saldaña-Tejeda
8. Medical Tourism and Multi-Level Regulation for MRT in the European Union
Walter G. Johnson and Diana M. Bowman
9. Asia
Tetsuya Ishii

Part III: Looking Forward
10. Future Technological Advancements
Kevin Doxzen
11. Placing MRT in the Evolution of Reproduction
Karinne Ludlow, Walter G. Johnson, and Diana M. Bowman

Index