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Forensic DNA Technology

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ISBN13: 9780873712651
ISBN: 087371265X
Published: July 1992
Publisher: Taylor & Francis Group
Country of Publication: UK
Format: Hardback
Price: Out of print



This book examines the legal and scientific issues relating to the implementation of DNA print technology in both the crime laboratory and the courtroom. It traces the underlying theory and historical development of this technology, as well as the methodology utilized in the Restriction Fragment Length Polymorphism (RFLP) and Polymerase Chain Reaction (PCR) techniques. The effect of environmental contaminants on the evidence and the statistical analysis of population genetics data as it relates to the potential of this technology for individualizing the donor of the sample are also addressed. Other topics include the proposed guidelines for using this technology in the crime laboratory, the perspectives of the prosecution and the defence, and the legal standards for determining the admissability and weight of such evidence at trial.;The issues of validation and the standards for intepretation of audioradiograms are considered with the aid of actual case work.;The contributors are Jan A. Witkowski, Roger Kahn, Michael L. Baird, Lawrence Mueller, George Sensabaugh, Cecilia Von Beroldingen, Bruce Budowle, Samuel Baechtel, Dwight E. Adams, William Thompson, Simon Ford, Rockne Harmon, Allan Hymer and Jan Bashinski.

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Contents:
Milestones in the Development of DNA Technology. An Introduction to DNA Structure and Genome Organization. Analysis of Forensic DNA Samples by Single Locus VNTR Probes. Population Genetics of Hypervariable Human DNA. Polymerase Chain Reaction; Application to the Analysis of Biological Evidence. Validation With Regard to Environmental Insults of the RFLP Procedure for Forensic Purposes. The Meaning of a Match: Sources of Ambiguity in the Interpretation of DNA Prints. General Admissibility Considerations for DNA Typing Evidence: Lets Learn from the Past and Let the Scientists Decide This Time Around. DNA Testing in Criminal Cases; A Defense Prospective. Managing the Implementation and Use of DNA Typing in the Crime Laboratory. Appendix. Glossary. Index.